Health Economics›Thyroid cancer medullary›Locally advanced or metastatic disease targeted therapy-naive

Locally advanced or metastatic disease targeted therapy-naive

Thyroid cancer medullary · 4 regimens

Cost estimates only — modelled on a typical patient (BSA 1.7 m², 70 kg, CrCl 90 mL/min) using the cheapest available formulary presentation. Excludes vial wastage, facility fees, supportive care, and infusion consumables. Not for billing, formulary decisions, or clinical use.

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Cost vs Efficacy · 2 points

Fully pricedPartial pricing

Regimen	Biomarker	Cost/cycle ↓	Cycle	PFS ↕	OS ↕	Est. cycles	Course cost ↕	Evidence
Cabozantinib monotherapy Variant #01	—	R 151 638	28d	16.8 mo	—	2	R 303 276 PFS proxy	1
Sorafenib monotherapy Variant #04	—	R 37 339	28d	~10.8 mo	—	~25	~R 549 414 PFS proxy · indirect	1
Selpercatinib monotherapy Variant #01 Partial	—	—	28d	—	—	2	—	1
Vandetanib monotherapy Variant #01 Partial	—	—	28d	16.8 mo	—	2	—	2

4 of 4 regimens shown