Non-small cell lung cancer · 13 regimens
Cost vs Efficacy · 5 points
| Regimen | Biomarker | Cost/cycle ↓ | Cycle | PFS ↕ | OS ↕ | Est. cycles | Course cost ↕ | Evidence |
|---|---|---|---|---|---|---|---|---|
Carboplatin, Pemetrexed, Bevacizumab Variant #01 | — | R 44 549 | 21d | ~6.8 mo | ~12.6 mo | ~5 | ~R 221 407 PFS proxy · indirect | 2 |
Pemetrexed and Bevacizumab Variant #01 | — | R 43 211 | 21d | — | ~23.3 mo | ~2 | ~R 86 422 PFS proxy · indirect | 1 |
Atezolizumab monotherapy Variant #01 | — | R 31 255 | 21d | — | 20.2 mo | 2 | R 62 509 PFS proxy | 2 |
Carboplatin and Pemetrexed Variant #01 | — | R 14 563 | 21d | 8.6 mo | 13.3 mo | 4 | R 58 251 PFS proxy | 6 |
Pemetrexed monotherapy Variant #01 | — | R 13 225 | 21d | — | 5.3 mo | 4 | R 52 900 PFS proxy | 1 |
Gemcitabine and Paclitaxel Variant #01 | — | R 5 224 | 21d | — | 9.8 mo | 6 | R 31 344 PFS proxy | 1 |
Carboplatin and Gemcitabine (GCb) Variant #01 | — | R 4 414 | 21d | 6.0 mo | 10.0 mo | 2 | R 8 829 PFS proxy | 7 |
Gemcitabine and Vinorelbine Variant #01 | — | R 4 259 | 21d | — | 6.7 mo | 2 | R 8 518 PFS proxy | 2 |
Cisplatin and Gemcitabine (GC) Variant #01 | — | R 3 933 | 21d | 6.0 mo | 10.4 mo | 6 | R 23 595 PFS proxy | 14 |
Docetaxel monotherapy Variant #02 | — | R 2 921 | 28d | — | 8.4 mo | 8 | R 23 372 PFS proxy | 2 |
Gemcitabine monotherapy Variant #01 | — | R 1 672 | 21d | — | 6.2 mo | 7 | R 11 705 PFS proxy | 4 |
Carboplatin and Paclitaxel (CP) Variant #02 | — | R 1 025 | 21d | 5.3 mo | 10.3 mo | 9 | R 9 222 PFS proxy | 32 |
Vinorelbine monotherapy Variant #01 | — | R 458 | 21d | — | 6.2 mo | 7 | R 3 203 PFS proxy | 3 |
13 of 13 regimens shown