Health Economics›Large granular lymphocytic leukemia›Initial therapy

Initial therapy

Large granular lymphocytic leukemia · 2 regimens

Cost estimates only — modelled on a typical patient (BSA 1.7 m², 70 kg, CrCl 90 mL/min) using the cheapest available formulary presentation. Excludes vial wastage, facility fees, supportive care, and infusion consumables. Not for billing, formulary decisions, or clinical use.

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Y-axis

Cost vs Efficacy

No data points — cost or PFS missing for current selection.

Regimen	Biomarker	Cost/cycle ↓	Cycle	PFS ↕	OS ↕	Est. cycles	Course cost ↕	Evidence
Cyclophosphamide monotherapy Variant #01	—	R 1 680	28d	—	~15.8 mo	~1	~R 1 680 PFS proxy · indirect	1
Methotrexate and Prednisone Variant #01 Partial	—	R 303	28d	—	—	~3	~R 743 indirect	—

2 of 2 regimens shown