Langerhans cell histiocytosis · 6 regimens
Cost vs Efficacy
| Regimen | Biomarker | Cost/cycle ↓ | Cycle | PFS ↕ | OS ↕ | Est. cycles | Course cost ↕ | Evidence |
|---|---|---|---|---|---|---|---|---|
Etoposide, Vinblastine, Prednisone Variant #01 Partial | — | R 14 511 | 42d | — | — | ~6 | ~R 24 880 indirect | — |
Vinblastine and Prednisone Variant #01 Partial | — | R 10 203 | 42d | — | — | ~6 | ~R 17 494 indirect | — |
Methotrexate, Vinblastine, Prednisone Variant #01 Partial | — | R 9 353 | 42d | — | — | ~1 | ~R 9 353 indirect | — |
Etoposide and Methylprednisolone Variant #01 | — | R 4 828 | 21d | — | — | ~8 | ~R 17 753 indirect | — |
Vinblastine and Methylprednisolone Variant #01 | — | R 4 426 | 7d | — | — | ~24 | ~R 37 642 indirect | — |
Cytarabine and Methotrexate (CYM) Variant #03 | — | R 649 | 21d | — | — | ~6 | ~R 3 893 indirect | — |
6 of 6 regimens shown