Kaposi sarcoma · 13 regimens
Cost vs Efficacy · 4 points
| Regimen | Biomarker | Cost/cycle ↓ | Cycle | PFS ↕ | OS ↕ | Est. cycles | Course cost ↕ | Evidence |
|---|---|---|---|---|---|---|---|---|
Bevacizumab monotherapy Variant #01 | — | R 19 082 | 14d | ~6.7 mo | ~19.6 mo | ~2 | ~R 38 164 PFS proxy · indirect | 10 |
Pegylated liposomal doxorubicin monotherapy Variant #02 | — | R 8 000 | 28d | ~4.2 mo | ~13.5 mo | ~6 | ~R 48 000 PFS proxy · indirect | 24 |
Pomalidomide monotherapy Variant #01 | — | R 4 782 | 28d | ~2.7 mo | — | ~2 | ~R 9 564 PFS proxy · indirect | 1 |
ABV (Vinblastine) Variant #01 Partial | — | R 1 895 | 28d | — | — | ~2 | ~R 3 790 indirect | — |
Etoposide monotherapy Variant #01 | — | R 1 231 | 28d | — | — | ~6 | ~R 7 386 indirect | — |
Paclitaxel monotherapy Variant #02 | — | R 734 | 28d | ~4.8 mo | ~12.0 mo | ~7 | ~R 5 141 PFS proxy · indirect | 85 |
ABV (Vincristine) Variant #01 Partial | — | R 389 | 14d | — | — | ~6 | ~R 2 332 indirect | — |
Bleomycin and Vincristine (BO) Variant #01 Partial | — | R 327 | 14d | — | — | ~1 | ~R 327 indirect | — |
Interferon alfa-2b monotherapy Variant #01 Partial | — | — | 28d | ~13.2 mo | — | ~6 | — | 2 |
Placebo Partial | — | — | — | ~1.3 mo | ~7.6 mo | — | — | 11 |
Alitretinoin monotherapy Variant #01 Partial | — | — | 84d | — | — | ~1 | — | — |
Interferon alfa-2a monotherapy Variant #01 Partial | — | — | 7d | ~5.4 mo | ~17.5 mo | ~2 | — | 10 |
Daunorubicin liposomal monotherapy Variant #01 Partial | — | — | 14d | — | — | ~2 | — | — |
13 of 13 regimens shown