Health Economics›Inherited coagulopathy›Factor VIII deficiency (Hemophilia A) with inhibitors all lines of therapy

Factor VIII deficiency (Hemophilia A) with inhibitors all lines of therapy

Inherited coagulopathy · 3 regimens

Cost estimates only — modelled on a typical patient (BSA 1.7 m², 70 kg, CrCl 90 mL/min) using the cheapest available formulary presentation. Excludes vial wastage, facility fees, supportive care, and infusion consumables. Not for billing, formulary decisions, or clinical use.

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Cost vs Efficacy

No data points — cost or PFS missing for current selection.

Regimen	Biomarker	Cost/cycle ↓	Cycle	PFS ↕	OS ↕	Est. cycles	Course cost ↕	Evidence
Rituximab monotherapy Variant #09 Partial	—	—	28d	~20.3 mo	—	~1	—	20
Observation Partial	—	—	—	~10.3 mo	~37.1 mo	—	—	65
Emicizumab monotherapy Partial	—	—	—	—	—	—	—	—

3 of 3 regimens shown