Health Economics›Head and neck cancer›Locally advanced disease induction

Locally advanced disease induction

Head and neck cancer · 4 regimens

Cost estimates only — modelled on a typical patient (BSA 1.7 m², 70 kg, CrCl 90 mL/min) using the cheapest available formulary presentation. Excludes vial wastage, facility fees, supportive care, and infusion consumables. Not for billing, formulary decisions, or clinical use.

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Cost vs Efficacy · 2 points

Fully pricedPartial pricing

Regimen	Biomarker	Cost/cycle ↓	Cycle	PFS ↕	OS ↕	Est. cycles	Course cost ↕	Evidence
DCF Variant #01	—	R 3 508	21d	12.8 mo	36.8 mo	2	R 7 015 PFS proxy	7
PCF Variant #01	—	R 2 300	—	—	—	~3	~R 6 899 indirect	—
Cisplatin and Fluorouracil (CF) Variant #01	—	R 1 235	28d	11.3 mo	9.0 mo	6	R 7 412 PFS proxy	8
No induction Partial	—	—	—	—	31.7 mo	—	—	2

4 of 4 regimens shown