Head and neck cancer · 17 regimens
Cost vs Efficacy · 2 points
| Regimen | Biomarker | Cost/cycle ↓ | Cycle | PFS ↕ | OS ↕ | Est. cycles | Course cost ↕ | Evidence |
|---|---|---|---|---|---|---|---|---|
Cetuximab and RT Variant #01 | — | R 101 572 | 49d | ~22.4 mo | ~46.0 mo | ~1 | ~R 101 572 PFS proxy · indirect | 4 |
Carboplatin, Fluorouracil, Cetuximab, RT Variant #01 | — | R 93 912 | 49d | ~37.9 mo | — | ~1 | ~R 93 912 PFS proxy · indirect | 1 |
Fluorouracil, Mitomycin, RT Variant #01 | — | R 5 186 | 56d | — | ~23.0 mo | ~1 | ~R 5 186 PFS proxy · indirect | 1 |
Carboplatin, Fluorouracil, RT Variant #01 | — | R 4 374 | 35d | — | — | ~1 | ~R 4 374 indirect | — |
Carboplatin and Paclitaxel (CP) and RT Variant #01 | — | R 3 809 | 35d | — | ~18.2 mo | ~1 | ~R 3 809 PFS proxy · indirect | 3 |
Carboplatin and RT Variant #01 | — | R 3 746 | 42d | — | ~22.4 mo | ~1 | ~R 3 746 PFS proxy · indirect | 1 |
Cisplatin and Paclitaxel (TP) and RT Variant #01 | — | R 2 425 | 21d | — | — | ~1 | ~R 2 425 PFS proxy · indirect | 1 |
Cisplatin, Nimotuzumab, RT Variant #01 Partial | — | R 2 059 | 49d | — | — | ~1 | ~R 2 059 PFS proxy · indirect | 1 |
Cisplatin and Fluorouracil (CF) and RT Variant #01 | — | R 1 774 | 17d | — | ~16.5 mo | ~1 | ~R 1 774 PFS proxy · indirect | 1 |
Paclitaxel and RT Variant #01 | — | R 1 714 | — | — | — | ~1 | ~R 1 714 indirect | — |
Bleomycin, Methotrexate, Vinblastine/RT Variant #01 Partial | — | R 1 647 | 14d | — | — | ~4 | ~R 6 588 indirect | — |
Docetaxel, Fluorouracil, Hydroxyurea, RT Variant #01 | — | R 1 536 | 14d | — | — | ~5 | ~R 7 680 PFS proxy · indirect | 1 |
Docetaxel and RT Variant #01 | — | R 1 298 | 49d | — | ~25.5 mo | ~1 | ~R 1 298 PFS proxy · indirect | 1 |
Fluorouracil and RT Variant #01 | — | R 809 | 42d | — | ~33.0 mo | ~1 | ~R 809 PFS proxy · indirect | — |
Fluorouracil, Hydroxyurea, RT Variant #01 | — | R 720 | 14d | — | — | ~7 | ~R 5 040 indirect | — |
Cisplatin and RT Variant #01 | — | R 588 | 49d | — | ~58.6 mo | ~1 | ~R 588 PFS proxy · indirect | 10 |
Radiation therapy N/A - radiation | — | — | 49d | — | ~29.3 mo | — | — | 4 |
17 of 17 regimens shown