Health Economics›Gastrointestinal stromal tumor›Metastatic or unresectable disease third-line

Metastatic or unresectable disease third-line

Gastrointestinal stromal tumor · 4 regimens

Cost estimates only — modelled on a typical patient (BSA 1.7 m², 70 kg, CrCl 90 mL/min) using the cheapest available formulary presentation. Excludes vial wastage, facility fees, supportive care, and infusion consumables. Not for billing, formulary decisions, or clinical use.

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Cost vs Efficacy · 3 points

Fully pricedPartial pricing

Regimen	Biomarker	Cost/cycle ↓	Cycle	PFS ↕	OS ↕	Est. cycles	Course cost ↕	Evidence
Regorafenib monotherapy Variant #06	—	R 307 423	28d	5.2 mo	—	6	R 1 844 535 PFS proxy	2
Cabozantinib monotherapy Variant #01	—	R 90 983	28d	~9.3 mo	~16.2 mo	~11	~R 1 000 811 PFS proxy · indirect	17
Sorafenib monotherapy Variant #04	—	R 37 339	28d	—	—	—	—	1
Pazopanib monotherapy Variant #01	—	R 22 754	28d	3.4 mo	—	4	R 91 014 PFS proxy	1

4 of 4 regimens shown