Cutaneous T-cell lymphoma · 14 regimens
Cost vs Efficacy · 4 points
| Regimen | Biomarker | Cost/cycle ↓ | Cycle | PFS ↕ | OS ↕ | Est. cycles | Course cost ↕ | Evidence |
|---|---|---|---|---|---|---|---|---|
Alemtuzumab monotherapy Variant #01 | — | R 132 218 | 7d | ~15.0 mo | — | ~66 | ~R 8 726 355 PFS proxy · indirect | — |
Brentuximab vedotin monotherapy Variant #01 | — | R 85 244 | 21d | ~16.7 mo | — | ~25 | ~R 2 131 097 PFS proxy · indirect | 1 |
Lenalidomide monotherapy N/A - secondary systemic drug | — | R 6 361 | 90d | ~39.0 mo | ~113.8 mo | ~14 | ~R 89 057 PFS proxy · indirect | 10 |
Bendamustine monotherapy Variant #01 | — | R 5 419 | — | ~16.5 mo | — | — | — | 2 |
Denileukin diftitox monotherapy N/A - secondary systemic drug | — | R 0 | 21d | — | — | — | — | — |
Pralatrexate monotherapy N/A - secondary systemic drug | — | R 0 | 49d | — | — | — | — | 1 |
Placebo Partial | — | — | — | ~4.2 mo | ~8.0 mo | — | — | 145 |
Belinostat monotherapy Variant #01 Partial | — | — | 21d | — | — | — | — | — |
Methotrexate monotherapy Partial | — | — | — | ~3.5 mo | — | — | — | 1 |
Bexarotene monotherapy Variant #01 Partial | — | — | 336d | ~3.5 mo | — | ~1 | — | 1 |
Bexarotene and Pralatrexate Variant #01 Partial | — | — | 28d | — | — | — | — | — |
Mogamulizumab monotherapy Variant #01 Partial | — | — | 7d | ~7.7 mo | — | ~34 | — | 1 |
Romidepsin monotherapy Variant #01 Partial | — | — | 28d | — | — | — | — | 1 |
Vorinostat monotherapy Variant #01 Partial | — | — | 28d | ~3.1 mo | — | ~4 | — | 1 |
14 of 14 regimens shown