Health Economics›Autologous HSCT›High dose therapy conditioning regimens all lines of therapy

High dose therapy conditioning regimens all lines of therapy

Autologous HSCT · 27 regimens

Cost estimates only — modelled on a typical patient (BSA 1.7 m², 70 kg, CrCl 90 mL/min) using the cheapest available formulary presentation. Excludes vial wastage, facility fees, supportive care, and infusion consumables. Not for billing, formulary decisions, or clinical use.

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Cost vs Efficacy · 2 points

Fully pricedPartial pricing

Regimen	Biomarker	Cost/cycle ↓	Cycle	PFS ↕	OS ↕	Est. cycles	Course cost ↕	Evidence
Bu/TT Variant #01 Partial	—	R 26 139	—	—	—	—	—	—
R-TBI/Cy Variant #01	—	R 24 768	—	—	—	—	—	—
R-BEAM Variant #01 Partial	—	R 22 812	—	—	—	—	—	—
BeEAM Variant #01	—	R 16 337	—	—	—	—	—	—
CBV-Mx Variant #01 Partial	—	R 15 375	—	—	—	—	—	—
Z-BEAM Variant #01 Partial	—	R 12 158	—	—	—	—	—	—
Etoposide and TBI Variant #01	—	R 8 617	—	—	—	—	—	—
Busulfan and Cyclophosphamide Variant #01	—	R 7 711	—	—	—	—	—	—
LEED Variant #01	—	R 7 064	—	—	—	—	—	—
V-BEAM Variant #01 Partial	—	R 6 993	—	—	—	—	—	—
CTCb Variant #01 Partial	—	R 6 280	—	—	~24.0 mo	—	—	1
Busulfan and Melphalan Variant #01	—	R 5 233	—	—	—	—	—	1
BEAM Variant #01 Partial	—	R 4 294	—	—	—	—	—	—
FEAM Variant #01 Partial	—	R 4 294	—	—	—	—	—	—
Bortezomib and Melphalan Variant #01	—	R 3 617	—	—	—	—	—	—
BEAC N/A - secondary systemic drug	—	R 3 241	—	—	—	—	—	—
CHUT Variant #01 Partial	—	R 3 005	—	—	—	—	—	—
Cyclophosphamide and TBI Variant #01	—	R 1 176	—	—	~90.0 mo	—	—	2
Melphalan monotherapy Variant #01	—	R 71	42d	~50.0 mo	~22.2 mo	~37	~R 2 636 PFS proxy · indirect	7
CBV N/A - secondary systemic drug Partial	—	R 43	—	—	—	—	—	4
Cyclophosphamide, Etoposide, TBI N/A - secondary systemic drug	—	R 23	—	—	—	—	—	—
Tandem melphalan Variant #03	—	R 0	—	~43.0 mo	—	—	—	8
Melphalan and TBI Variant #01	—	R 0	—	—	—	—	—	—
Bu/TT/Cy N/A - secondary systemic drug	—	R 0	—	—	—	—	—	—
TAM6 Variant #01	—	R 0	—	—	—	—	—	—
TBI Variant #01 Partial	—	—	—	—	—	—	—	4
BCNU/TT Variant #01 Partial	—	—	—	—	—	—	—	—

27 of 27 regimens shown